Sclerotinia sclerotiorum (Lib.) de Bary is a broad host-range fungus that infects an inclusive array of plant species and afflicts significant yield losses globally.Despite being a notorious pathogen, it has an uncomplicated life cycle consisting of either basal infection from myceliogenically germinated sclerotia or aerial infection from ascospore
Introduction Malaria is associated with high morbidity during pregnancy.Homozygous sickle cell pregnant Cooler Bag women are even more exposed during complicated malaria.The objective of the study was to evaluate the maternal and fetal morbidity of homozygous sickle cell pregnant pregnant women with complicated malaria.Methods We conducted a retros
Background Most patients with advanced melanomas relapse after checkpoint blockade therapy.Thus, immunotherapies are needed that can be applied safely early, in the adjuvant setting.Seviprotimut-L is a vaccine containing human melanoma antigens, plus alum.To assess the efficacy of seviprotimut-L, the Melanoma Antigen Vaccine Immunotherapy Study (MA
VISTA (PD-1H) is an immune regulatory molecule considered part of the next wave of immuno-oncology targets.VISTA is an immunoglobulin (Ig) superfamily cell surface molecule mainly expressed on myeloid cells, and to some extent on NK cells and T cells.In previous preclinical studies, some VISTA-targeting antibodies provided immune inhibitory signals
A 52 year-old male presented with neck pain after undergoing thyroidectomy for a goiter three weeks prior which was complicated by a neck hematoma requiring evacuation.Computed tomography (CT) scan showed a neck hematoma requiring evacuation and he received desmopressin with cessation of bleeding.Coagulation studies were normal.He returned eighteen